Brønsted acid‐catalyzed Reactions of Unprotected <i>N</i> ‐heterocycles with Aryl/Aryl Diazoalkanes
نویسندگان
چکیده
The chemoselective C−H functionalization of unprotected N-heterocycles is a challenging task in organic synthesis. Herein, we report on Brønsted-acid catalyzed reaction aryl/aryl diazoalkanes with to selectively allow for at the C3-position under mild conditions and short time without need protecting groups. general applicability this method was further expanded towards protected indole pyrrole heterocycles.
منابع مشابه
Small heterocycles in multicomponent reactions.
Benjamin H. Rotstein,†,‡ Serge Zaretsky,† Vishal Rai,†,§ and Andrei K. Yudin*,† †Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario Canada, M5S 3H6 ‡Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, and Department of Radiology, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 021...
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ژورنال
عنوان ژورنال: Asian Journal of Organic Chemistry
سال: 2021
ISSN: ['2193-5815', '2193-5807']
DOI: https://doi.org/10.1002/ajoc.202000709